{"product_id":"acetyl-hexapeptide-1-melitane","title":"Acetyl Hexapeptide-1 (Melitane)","description":"\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eAcetyl Hexapeptide-1, also known as Melitane\u003cmeta charset=\"utf-8\"\u003e®, is a biomimetic peptide antagonist of the α-MSH (α-Melanocyte-Stimulating Hormone). \u003cmeta charset=\"UTF-8\"\u003eThe α-MSH regulates melanin synthesis via the activation of its receptor MC1-R. Because of its affinity with the receptor MC1-R, Acetyl Hexapeptide-1 can be used as a natural photo-protector and as an inflammation modulator.\u003c\/span\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNatural Photo-protection Factor:\u003c\/strong\u003e Melitane® mimics the activity of the α-MSH and stimulates melanocyte activity as well as melanin pigment production.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammation Modulation Factor:\u003c\/strong\u003e Acetyl Hexapeptide-1 limits the expression of biochemical inflammation mediators such as IL-1, IL-8, PGE2 and Rantes via the activation of MC1-R receptor and provides significant protection against UV-induced erythema.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBy stimulating the melanin synthesis through a natural pathway and by preventing the excessive production of pro-inflammatory cytokines, Melitane® represents an ideal complement to the skin’s own levels of natural melanin and strengthens the skin’s defenses against the harmful effects of sunshine and reduces the potential pro-inflammatory consequences.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eChemical Properties:\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eINCI name:\u003c\/strong\u003e Acetyl Hexapeptide-1\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eCAS#:\u003c\/strong\u003e 448944-47-6\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eFormula:\u003c\/strong\u003e  \u003c\/span\u003eC\u003csub\u003e43\u003c\/sub\u003eH\u003csub\u003e59\u003c\/sub\u003eN\u003csub\u003e13\u003c\/sub\u003eO\u003csub\u003e7\u003c\/sub\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eSequence:\u003c\/strong\u003e Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH\u003csub\u003e2\u003c\/sub\u003e; XAHFRW\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eM.W.:\u003c\/strong\u003e 870.01 g\/mol\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e: \u003cmeta charset=\"UTF-8\"\u003eMelitane®\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e keep away from moisture, -20C for 3 years\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cbr\u003e\u003c\/h3\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003eEven if gray hair can be a fashion statement, many people desire lustrous colorful hair. As we age, the hair follicles produce less melanin, the pigment responsible for hair color, so progressively hair become gray.\u003c\/p\u003e\n\u003cp\u003eHair follicles produce the hair fiber that becomes pigmented as a result of melanin synthesis and its transfer from melanocytes into keratinocytes. To fight back hair graying, Unipex has developed Acetyl Hexapeptide-1, a biomimetic peptide derived from alpha-MSH.\u003c\/p\u003e\n\u003cp\u003eAcetyl Hexapeptide-1 (sequence: Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH\u003csub\u003e2\u003c\/sub\u003e; XAHFRW) stimulates melanin synthesis by melanocytes and also favors melanin transfer from melanocytes into keratinocytes. Moreover, Acetyl Hexapeptide-1 obtains outstanding results in ex vivo experiments on hair.\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e\u003cspan\u003eIt decreases the number of white and low-pigmented cells and increases the number of moderate and highly-pigmented cells in hair bulbs. Acetyl Hexapeptide-1 is also used in a peptide-based MelinOIL™ for preparing skin for sun exposure and protection from UV-induced photoaging.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"QUALITIDE","offers":[{"title":"100 mg","offer_id":49498658341104,"sku":"QT-1029-100MG","price":138.0,"currency_code":"USD","in_stock":false},{"title":"1 g","offer_id":49498658373872,"sku":"QT-1029-1G","price":988.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0831\/0276\/1200\/files\/QT-1029_AcetylHexapeptide-1-100mg.png?v=1775256491","url":"https:\/\/shopsmartpicks.store\/products\/acetyl-hexapeptide-1-melitane","provider":"Shopsmartpicks","version":"1.0","type":"link"}